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Beyond glycemic control, these medications slow gastric emptying (though this effect may diminish over time), which prolongs the feeling of fullness after meals

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Retatrutide: drievoudige agonist ( GIP/GLP-1/glucagon ), waardoor in vroege studies grotere en snellere gewichtsreducties werden gezien dan met enkelvoudige of dubbele incretine-agonisten

When the effects of age on renal function are taken into account, age alone did not have a clinically meaningful impact on the pharmacokinetics of sitagliptin based on a population pharmacokinetic analysis
