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Int J Mol Sci (2021) 22(7):3330

or LTI scheme for diabetes

The SELECT trial further showed that once-weekly semaglutide reduced first-event MACE by 20% in adults with obesity and prior cerebrovascular disease, extending cardiovascular protection beyond diabetes [319, 320]

While the evidence is not yet definitive, some researchers suggest that long-term exposure to GLP-1 drugs could potentially influence the activity of the guts L-cells the cells responsible for producing natural GLP-1 and related hormones such as GLP-2, which helps maintain the integrity of the intestinal lining
