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Nuclear factor kappa B (NF-B), NH2-terminal Jun kinases, and p53 MAPK are transcriptionally regulated pathways that have been considered one of the most important stress-signaling pathways, and oxidative stress plays a role in the development of type 2 diabetes mellitus through their involvement (14)

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Observational data suggest that muscle wasting is not disproportionately accelerated by GLP-1RAs compared to other weight-loss interventions

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