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Glucocorticoids suppress GLP-1 secretion: possible contribution to their diabetogenic effects

In our experience, these may include patient demographics (eg, age, sex, and ethnicity)

To manage symptoms effectively: Start with a low dose and titrate slowly Encourage smaller, low-fat meals Consider changing the dosing schedule or formulation Evaluate other GI causes like gastroparesis if symptoms linger Having regular check-ins helps clinicians identify tolerability issues early and adapt treatment accordingly

In a six-month clinical trial, a GLP-1 drug called liraglutide was shown to slow the progression of the disease and improve the cerebral metabolic rate of glucose (CMRglc), which is a measurement of glucose metabolism in the brain important for normal cognitive function