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Both sexes are subject to the neurochemical effects on reward pathways, but hormonal factors create different clinical presentations

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Cardiovascular disease is increased in type 2 diabetes, and hyperglyceamia is a critical promoter during the development of cardiovascular diseases

For weight management, NICE has approved semaglutide (Wegovy) for adults with a BMI of at least 35 kg/m (or 30 kg/m with weight-related comorbidities) within specialist weight management services