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The primary focus of current lawsuits against manufacturers of GLP-1 agonists is severe gastrointestinal side effects, including: Gastroparesis : Often referred to as stomach paralysis, this condition causes delayed stomach emptying and can lead to: Severe nausea and vomiting Abdominal pain and bloating Loss of appetite and weight loss Malnutrition and dehydration Difficulty eating and absorbing nutrients Ileus : Similar to gastroparesis but affecting the small intestine, ileus occurs when the intestinal muscles fail to move food properly through the digestive tract

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There were no significant differences in the total pregnancy rate or IVF (in vitro fertilization) pregnancy rate between those prescribed a GLP-1 receptor agonist (RA) vs

Interestingly, the combined application of GLP-1 and GIP resulted in a greater decrease in bone resorption than was seen with these hormones alone (Frias et al., 2018)