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Description
Age Factor: Mature skin might not bounce back as quickly as younger skin
Patients not on treatment or on other antihyperglycemic agents entered a run-in treatment period of up to 12 weeks duration with metformin monotherapy (dose of greater than or equal to 1500 mg per day) which included washout of medications other than metformin, if applicable

It tells FDA staff how to handle certain categories of products at the border

That question has largely been answered
