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Microdosing represents an alternative approach where patients start at even lower doses than the standard 2.5mg, sometimes beginning at 1mg or 1.5mg weekly and increasing in smaller increments

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For a broader overview of how these medications fit into weight management, see what GLP-1 treatment is and how it can help with weight loss goals

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This development occurs as Novo Nordisk and Eli Lilly continue to defend against thousands of lawsuits claiming they failed to warn about other serious risks associated with GLP-1 drugs, including gastroparesis and vision loss

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Keywords: tirzepatide, postmarketing surveillance, drug safety, adverse events Introduction Tirzepatide, a novel dual agonist targeting glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors marketed as Zepbound by its manufacturer Eli Lilly and Company, has shown significant efficacy in managing type 2 diabetes mellitus (T2DM) and obesity, as demonstrated in key clinical trials such as SURPASS [1] and SURMOUNT [2]

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