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They are both usually administered as weekly injections

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Acute administration of the GLP-1RA exenatide resulted in reduced feelings of hunger, which is due to an increase in functional connectivity of the nucleus tractus solitarius with the hypothalamus and thalamus [129]

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This suggests the drug is doing more than just reducing calorie intake

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Clinical trial data shows only 4.2% of participants discontinued due to side effects after week 24

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