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Decongestants like pseudoephedrine (Sudafed) and phenylephrine can be used safely with Semaglutide, though these medications may increase heart rate slightly

Persistent diarrhoea with blood, mucus, nocturnal symptoms or weight loss requires prompt medical evaluation to exclude other causes

Occurrence of nausea, vomiting and diarrhoea reported as adverse events in clinical trials studying glucagonlike peptide1 receptor agonists: a systematic analysis of published clinical trials

How PlexusDx Supports a More Personalized Approach Genetic predispositions in GLP-1 receptor signaling, GIPR pathways, and metabolic genes (such as FTO and MC4R variants) may provide context for why some patients experience better appetite suppression or weight loss with specific GLP-1 formulations