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42 Research has shown that GLP-1RA can trigger the AMPK pathway, resulting in anti-inflammatory outcomes

Sitagliptin phosphate: A DPP-4 inhibitor for the treatment of type 2 diabetes mellitus

Several factors may explain why CVOTs have not demonstrated more robust or statistically significant results with combination therapy

Similar to our results, some studies [21, 22] also indicated that GLP-1 receptor agonists had a positive effect on the heart and enhanced cardiac function