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Clinical Evidence for GLP-1 Therapy and Weight Management Clinical trials (STEP 14, SUSTAIN trials) demonstrate that GLP-1 receptor agonists reduce body weight, improve glycemic control, and may lower cardiovascular risk in adults with overweight, obesity, or type 2 diabetes

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et al., Dapagliflozin in Patients with Chronic Kidney Disease, DAPA-CKD, N Engl J Med 2020 Oct 8 ;383(15):1436-1446 22

More studies are needed to confirm these findings, but on the basis of our experience, we suggest that the GLP-1 agonist semaglutide is considered as a possible treatment for obese patients with T2DM and psoriasis