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doi: 10.1007/s00592-018-1134-y 46 BenhalimaKMathiesenERPaldaniusPMMathieuC

Indeed, a very impressive number of randomized controlled clinical trials (RCTs) and systematic reviews provided robust evidence on the effectiveness of GLP-1RA in PCOS as a new, appealing approach, producing both satisfactory and permanent weight loss, and improvement of insulin resistance at the same time

These approaches focus on moderating the rate of weight loss and maintaining gallbladder function, though it should be noted that there is no official link established that these interventions definitively prevent gallstones in patients taking GLP-1 medications

Rapid weight loss can lead to a temporary spike in the waste product uric acid created when the body breaks down chemicals called purines in food and drinks that raises the risk of gout, he said