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These can vary widely from person to person

VAT analysis consisted of the measurement of the adipose tissue within the abdominal cavity, excluding adipose tissue outside the abdominal skeletal muscles and adipose tissue and lipids within the cavity and posterior of the spine and back muscles

The further synergistic combination approach with other gastrointestinal hormones and creation of dual GIP/GLP-1 receptor agonists, such as tirzepatide and GLP-1/GIP/glucagon receptor triagonist, retatrutide, has shown unprecedented pharmacologically achieved weight loss with further cardiometabolic benefits in both obesity and T2DM

Mazdutide has been evaluated in MASH-specific substudies showing liver fat reduction by MRI-PDFF exceeding 40% from baselinecomparable to survodutide's Phase 2 hepatic data