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observed significant between-group differences in hippocampal glutamate uptake between diabetic and control mice (F 2,14 = 10.84, p = 0.0014) wherein diabetic mice had significantly lower glutamate uptake.Reference Zanotto, Hansen and Galland 49 Following GLP-1 RA treatment, there was a significant reversal in glutamate uptake impairment wherein a 68.3% increase in glutamatergic metabolism was observed compared to diabetic rats that received negative control (p = 0.0005)

Preparing Your Thigh and Managing Injection Discomfort Clean the injection site with an alcohol wipe and allow it to dry completelywet skin creates stinging during needle insertion and compromises sterile technique