![tirzepatide surpass-5 Efficacy of in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1 Effect of Subcutaneous Tirzepatide vs](https://www.researchgate.net/publication/363201315/figure/fig3/AS:11431281082605778@1662084799021/Efficacy-of-tirzepatide-in-phase-2-GPGB-14-and-phase-3-SURPASS-1-to-5-15-19.png)
tirzepatide surpass-5 Efficacy of in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1 Effect of Subcutaneous Tirzepatide vs
Description
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![tirzepatide surpass-5 Efficacy of in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1 Effect of Subcutaneous Tirzepatide vs](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/734a/8826179/abb5737a6843/jama-e220078-g001.jpg)
Over half of the patients on the 10 mg dose and 63% on the 15 mg dose lost more than 20% of their body weight
![tirzepatide surpass-5 Efficacy of in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1 Effect of Subcutaneous Tirzepatide vs](https://medicaldialogues.in/h-upload/2021/10/19/162266-causes-of-diabetes.jpg)
The initial dose is typically 2.5 mg, administered once weekly, allowing the body to adjust before increasing the amount
![tirzepatide surpass-5 Efficacy of in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1 Effect of Subcutaneous Tirzepatide vs](https://www.nejm.org/cms/asset/67482ba8-0712-42b2-8a78-c184135fcbe8/nejmoa2416394_f1.jpg)
Stop antihistamines 7 days prior to testing
![tirzepatide surpass-5 Efficacy of in phase 2 (GPGB; [14]) and phase 3 (SURPASS-1 Effect of Subcutaneous Tirzepatide vs](https://img1.wsimg.com/isteam/ip/d7b9a298-03c9-4909-9ceb-c0fdf5784a16/Tirz%20image.png/:/rs=w:1280)
