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Prescription GLP-1 Medications Drugs like Ozempic, Wegovy, and Mounjaro contain synthetic GLP-1 receptor agonistspharmaceutical compounds that directly activate the same receptors natural GLP-1 activates

Glucosedependent insulinotropic polypeptide promotes beta(INS1) cell survival via cyclic adenosine monophosphatemediated caspase3 inhibition and regulation of p38 mitogenactivated protein kinase

A joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society explicitly states that restrictive eating disorder is a general contraindication to GLP-1 use and that individuals with a history of eating disorders should be referred to an eating disorders specialist before these medications are prescribed ( Mozaffarian et al., Am J Clinical Nutrition, 2025 )