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This concern applies to any rapid weight loss method during breastfeeding, not just GLP-1 medications

The "Patent Term Adjustments" tab shows the applicable dates, in this case: Filing or 371(c) Date: 08-11-2004 Issue Date of Patent: 06-06-2006 and also Total PTA Adjustments: 162 As this is an "old" application, it falls under the old rules which gave back days for USPTO caused delays (in some cases)

Tirzepatide is the first agent of its dual-incretin class to reach regulatory approval and is the subject of an extensive Phase 3 clinical trial program in adult human participants, with results published in The New England Journal of Medicine , The Lancet , and other peer-reviewed journals

A phase 1 multiple-ascending dose study of tirzepatide in Japanese participants with type 2 diabetes