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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Kappe C., Tracy L

This is substantiated by two large, randomized placebo-controlled trials, the Womens Health Initiative study 11 and the Heart and Estrogen/Progestin Replacement study 12 that found a significant reduction in the incidence of diabetes in women assigned to menopausal estrogen therapy, thus providing evidence for the antidiabetic action of estrogen in women