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[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Kreymann B, Ghatei MA, Domin J, Kanse S, Bloom SR

Results Prolonged GLP-1R Signalling Stimulates Glycolysis via Up-Regulation of Glycolytic Enzymes GLP-1 requires the presence of glucose for stimulation of insulin secretion 14

Mechanism of Action: When semaglutide binds to GLP-1 receptors, it stimulates the production of insulin while inhibiting the release of glucagon

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