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The results were significant: Average weight loss of 20.7% of starting body weight over a span of 72 weeks among participants who stayed on treatment, compared to 17.5% with the standard 2.4 mg dose

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Furthermore, the trajectory of the weight loss curves suggested that at 48 weeks the plateau of weight was not yet reached and all the participants in the 8 and 12 mg had a weight reduction of 5% or more, which is currently the minimum threshold for efficacy [64]