does semaglutide shrink your heart and the Heart: clinical insights from the SELECT Trial Are Weight Loss Medications Shrinking

RELEVANCE: Older adults are at higher risk of frailty, sarcopenia, dehydration, and nutritional decline

Discover Dripping Springs, Texasa charming Hill Country getaway with rich history, scenic parks & vibrant culture

Outlook for 2030 By 2030, obesity pharmacotherapy will likely be divided into three dominant segments: oral therapies (Orforglipron), monthly injectables (Berobenatide and MariTide), and high-efficacy multi-agonists (Retatrutide, Amycretin, and CagriSema)

Genetically-predicted GLP1R expression (the target of GLP-1 RAs) showed an inverse association with background [odds ratio (OR)=0.83, 95% CI, 0.710.97] and severe nonproliferative DR (OR=0.72, 95% CI, 0.530.98), and a non-significant association with overall (OR=0.97, 95% CI, 0.921.03) and proliferative DR (OR=0.98, 95% CI, 0.911.05)