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Management of bile acid malabsorption using low-fat dietary interventions: a useful strategy applicable to some patients with diarrhoea-predominant irritable bowel syndrome

So it was a kind of off-target observation when it was used for individuals with diabetes to then start studying it for obesity

This definition of need implies the preemptive update of deficiency prior to ingestion, which can indeed occur through sensory cognition and anticipation of the future and may be advantageous for survival [52]

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