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We know that it increases the disease risk. Studies have linked weight cycling to cardiovascular disease and diabetes, among other health issues

GLP-1 medications simulate the GLP-1 hormone thats naturally produced in the small intestine and has receptors throughout the bodyincluding, notably, the brain

Desai DD, Sikora M, Nohria A, et al

Long-term outcomes after bariatric surgery: A systematic review and metaanalysis of weight loss at 10 or more years for all bariatric procedures and a single-centre review of 20-year outcomes after adjustable gastric banding
