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There was no significant change in BMI within the exenatide group at 12 weeks, indicating that the effect on intracranial pressure was not driven by reduction in body weight, but likely by direct effect of exenatide to modulate intracranial pressure at the choroid plexus

Administration of prebiotics, non-digestible food ingredients that stimulate the growth of specific organisms of the microbiota, increased GLP-1 concentrations, correlating with appetite, fat mass, and hepatic insulin resistance 5

The conversion of tryptophan to 5-hydroxytryptophan is facilitated by the rate-limiting enzyme tryptophan hydroxylase (TPH) [19, 20]
Estradiol inhibits the activation of cell death caused by ROS (209)
