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As mentioned above, DPP-4 inhibitors can increase endogenous GLP-1 levels by suppressing GLP-1 degradation

Normally, compounding this medication isnt permitted, but due to national shortages, the FDA temporarily allowed it

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Method A literature search was performed in PubMed/MEDLINE, Scopus, Web of Science, and Google Scholar during March 2025September 2025, using combinations of the following terms: GLP-1 receptor, GLP-1R agonist, GLP-1 signalling, semaglutide, liraglutide, exenatide, dulaglutide, salivary glands, xerostomia, hyposalivation, oral adverse effects, biased agonism, -arrestin, cAMP, GPCR signaling, albumin binding, pharmacovigilance