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If you have Type 1 diabetes or advanced Type 2 diabetes with severely depleted beta cells, GLP-1 agonists alone will not adequately control your blood sugar
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Beyond weight reduction, the trial met several key secondary metabolic endpoints

As evidence of the efficacy of SGLT-2 inhibitors continued to grow, trials on these drugs have expanded their study populations from diabetes patients only to also include patients with HF or CKD in the absence of diabetes
