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This depolarization is propagated through voltage-dependent Calcium and Sodium channels, which currents lead to the discharge of the hormones containing vesicles (72)

10.1016/j.cellsig.2009.03.009 [DOI] [PMC free article] [PubMed] [Google Scholar] Schabath M

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This guided pathway balances tolerability with the therapeutic benefits these agents provide, ensuring patients have clear, actionable steps and know when to seek help.
