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It is commonly paired with rehmannia root, a powerful combination shown to increase GLP-1 levles

When activated, these hormones signal to the brain that the body is full, reducing hunger and promoting satiety

doi: 10.1016/j.peptides.2018.09.002 139 HuangJZhaoJGengXChuWLiSChenZJet al

Conversely, acute chemogenetic activation of those neurons fails to increase, and rather transiently reduces, energy expenditure [357]
