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In a study of two psoriasis patients with diabetes, liraglutide therapy for 6 weeks resulted in rapid clinical improvement, characterized by increased circulating i NKT cells and they also demonstrated in vitro that GLP-1 induced a dose-dependent reduction of cytokine secretion from i NKT cells [77]

Owing to glucagons hyperglycaemic and insulin-suppressing effects, the glucagon receptor (GcgR) has historically been a prime target for pharmacological suppression rather than activation
Salvio, G

SURMOUNT-5 was the head-to-head trial against semaglutide (the active ingredient in Wegovy and Ozempic)
