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Fourthly, while the intestine is the dominant source of circulating serotonin, future studies will be required to determine whether intestinally derived serotonin is the mediator of metabolic and hormonal changes characteristic of PBH and whether neural signaling is required

Ketogenic Diet and Health The beneficial weight loss effects of the ketogenic diet would be questionable if the diet had a detrimental effect on the body

Knockout of MAGEL2 reduces leptin sensitivity and inhibits POMC neurons activity, causing disruption of hypothalamic feeding circuits, hyperphagia and obesity [163]