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Methods This real-world, retrospective, observational cohort study included adults with obesity or overweight with1 obesity-related complication treated with semaglutide 2.4 mg identified in a large US claims and medical record database (December 15, 2020, through May 30, 2024)

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That exceeds tirzepatide's 22.5% and semaglutide's 15-17%

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Two emerging peptides, MOTS-c and Retatrutide, take very different approaches

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