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Quality, formulation, and safety can vary

however, gender- and age-specific responses, as well as concurrent medication use (eg, metformin), might influence outcomes

The elimination half-life of retatrutide is considered comparable to other long-acting receptor agonists such as semaglutide and tirzepatide
Several human studies showed beneficial effects of intermittent fasting (e.g., Ramadan fasting 16,17,18 ), and time-restricted eating 19 in subjects with metabolic syndrome