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included 41 patients with newly diagnosed DM2 and high risk of CV events with CAD, showed the effect of the combination of liraglutide and metformin on the lipid subfractions and markers of low-grade inflammation

Regarding cardiovascular outcomes, the EXSCEL trial showed that exenatide extended-release was noninferior but not superior to placebo for major adverse cardiovascular events

doi: 10.2337/dc24-S009 [DOI] [PMC free article] [PubMed] [Google Scholar] 14

In a six-month clinical trial, a GLP-1 drug called liraglutide was shown to slow the progression of the disease and improve the cerebral metabolic rate of glucose (CMRglc), which is a measurement of glucose metabolism in the brain important for normal cognitive function
