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Description
12.3 Pharmacokinetics Absorption Phentermine Upon oral administration of a single phentermine and topiramate extended-release capsule 15 mg/92 mg, the resulting mean plasma phentermine maximum concentration (Cmax), time to Cmax (Tmax), area under the concentration curve from time zero to the last time with measurable concentration (AUC0-t), and area under the concentration curve from time zero to infinity (AUC0) are 49.1 ng/mL, 6 hr, 1,990 nghr/mL, and 2,000 nghr/mL, respectively
This can repeat many times a night, often without the sleeper remembering it
Research by the U.S
Do not take two doses within 8 hours
