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Future trends to watch include how value-based contracting (rebates/tie-ins from IRA) might alter PBM incentives, whether new guidelines broaden obesity indications, and how consumer affordability programs adapt to PBM pressures

GLP-1 receptor agonistsincluding semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda)along with tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, have transformed the management of type 2 diabetes and obesity

At the same time, another study linking UPF consumption to early-onset colorectal cancer in women was contested, as experts said the study showed an association, not causation

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