how many pounds can you lose with tirzepatide Help Weight? Your First 3 Months on

Available at: (Accessed: 27 February 2026) Semaglutide is highly effective for weight loss, with 2.4 mg once weekly injections, alongside appropriate diet and exercise, reducing mean body weight by 16% after use for 68 weeks

Tirzepatide itself shows no direct nephrotoxicity, but the dehydration risk from GI side effects warrants periodic kidney function checks

J., Basagoiti-Carreo, B., Sanz-Velasco, A., Serrano-Moreno, C

Additionally, if you develop symptoms suggestive of gallbladder diseasesuch as right upper abdominal pain, particularly after eating fatty foods, accompanied by nausea or jaundicecontact your GP, as rapid weight loss can increase the risk of gallstones, a warning highlighted in the MHRA safety information for GLP-1 receptor agonists