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You shouldnt take these medications if you: Are pregnant, breastfeeding, or trying to get pregnant Have a family or personal history of medullary thyroid cancer or multiple endocrine neoplasia type 2 (MEN 2) Have a known allergy to any ingredients in the medication Have a personal or family history of pancreatitis GLP-1 agonists cost and accessibility While these drugs can be highly effective, they can also be expensive

How do emerging regulations and innovative players change the landscape

[12] Metformin: Anchor in the GLP-1 RA Care Continuum Journey The mechanistic, real-world, clinical trials and pharmacovigilance evidence landscape suggests metformin as the potential anchor pharmacological agent across the entire GLP-1 RA care continuum, during therapy and beyond.Table 1 summarises the key potential outcome benefits at each phase

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