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Wegovy is initiated at 0.25 mg weekly and gradually titrated to the target dose of 2.4 mg weekly as tolerated

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Fixed dose combinations with metformin are widely used

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GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca 2+ channel-dependent exocytosis

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Measuring bilirubin levels helps assess liver function and red blood cell turnover

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