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Moreover, postprandial GLP-1 response was also impaired in patients with ileostomy (Robertson et al

Classification of DPP-4 Inhibitors As an oral antidiabetic drug, the Dipeptidyl peptidase-4 inhibitors (DPP-4) class plays an important role in treating type 2 diabetes mellitus (T2DM) [1]

In addition to inducing insulin release, GLP-1R agonism can improve function and prevent exhaustion of pancreatic cells on a transcriptional level by stimulating multiple pro-proliferative and anti-apoptotic pathways, while optimising intracellular metabolism (Figure 1)

The body of evidence across multiple studies in various countries is conclusive that treatment with GLP-1 medications for type 2 diabetes and/or overweight/obesity is strongly associated with an elevated risk of developing NAION