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These may include: Upset stomach Heartburn Abdominal pain Vomiting Nausea Constipation Diarrhea Dizziness Fatigue Mild symptoms tend to resolve once the body starts to get used to the medication

Although generally safe, risks to also consider are allergic reactions, use during pregnancy, and low blood sugar levels.7 The mechanism of GLP-1 & GIP agonist has offered a multifaceted approach to treating both type 2 diabetes and obesity

Prediabetes affects roughly 38% of the population, and most do not know they have it

Higher mean age and baseline SBP, greater use of anti-hypertensive medications, longer T2D duration, and reduction in insulin daily dose might have contributed to explain the difference observed in the impact of weight loss on SBP reduction in these trials, although direct GLP-1R- and GIP-R-mediated effects could also be considered [77]