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2 Svetlana Mojsov, a chemist at Rockefeller University and pioneer in the field of GLP-1 research, had been studying glucagon for years when she first identified the cleavage sites in preproglucagon that give rise to biologically active GLP-1

Clinical evidence, encompassing trials, epidemiological investigations, and findings from animal toxicology and histological studies, has revealed potential associations between GLP-1RAs and the risk of neuroendocrine tumors and exocrine pancreatic dysplasia, with some evidence suggesting an increased risk of pancreatic cancer [6]
[Crossref] [PubMed] Mollan SP, Mitchell JL, Yiangou A, et al

Without a provider review, these contraindications may not be identified before treatment begins