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Description
This review explores the complex interplay between hyperkalemia and the use of guideline-directed medical therapies (GDMT), such as reninangiotensinaldosterone system inhibitors (RAASi) and steroidal mineralocorticoid receptor antagonists (sMRAs), including spironolactone and eplerenone, which are currently recommended in guidelines for improving outcomes in heart failure with reduced ejection fraction (HFrEF)

Consuming protein-rich meals, such as those containing eggs, lean meats, or plant-based proteins, can stimulate the release of GLP-1, helping to promote satiety and stabilize blood sugar levels

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GLP-1 medications alter intestinal motility and secretion, causing diarrhea in some users
