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After matching, patients who were not on GLP-1Ra were twice as likely to develop end-stage renal disease or dialysis dependence in 5 years after diagnosis compared to patients using GLP-1 agonists (OR 2.35, 95% CI 1.39,3.976)

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Peptide Structure Semaglutide is a synthetic analogue of GLP-1, modified to resist degradation, thereby lasting longer and being more effective

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