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Description
Manufacturers Amgen, AstraZeneca and Structure Therapeutics, among others, have anti-obesity drugs in the pipeline
Healthcare professionals must differentiate between common side effects and serious adverse reactions
Combining GLP-1 with estrogen into a stable conjugate that stimulates all GLP-1R-expressing cells but only those estrogen receptor-expressing cells that contain GLP-1R leads to better glycemic control and synergistic weight loss, as well as a reduction in food reward, the latter 2 mediated by the CNS (42, 43)
It is FDA-approved for persistent weight management
