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These decreases in body weight were not without costs, as semaglutide frequently caused gastrointestinal related side effects in patients
Tirzepatide is a 39-amino acid synthetic peptide with agonist activity at both the GIP and GLP-1 receptors

It plays a vital role in stimulating insulin secretion, slowing gastric emptying, and reducing appetite, thus helping maintain balanced blood sugar levels and supporting weight management

The ACCORD Study Group
