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Understanding its effects establishes the baseline against which all subsequent escalations are measured

The rate of weight loss may also influence the degree of cold intolerance, though this observation is primarily based on clinical experience rather than controlled studies

Therefore, while GLP-1RAs may represent a promising therapeutic option for managing psoriasis, further high-quality studies are needed to distinguish whether the therapeutic effects of GLP-1RAs originate from the direct regulation of immune cells or improvements in comorbidities such as obesity or diabetes

KL: Data curation, Formal analysis, Investigation, Validation, Writing original draft
