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Description
Gastrointestinal adverse effects are common with tirzepatide
The dry powder takes up about 60% of the volume of the vial

Additionally, the proximity of the rectum to the urethra (particularly in women) means that prolonged constipation increases the bacterial load near the urinary opening

LY3298176 activated both GIP and GLP-1 receptor signaling in vitro and showed glucose-dependent insulin secretion and improved glucose tolerance by acting on both GIP and GLP-1 receptors in mice
