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Description
Retatrutide is one of the most promising new weight-loss and metabolic health drugs currently in clinical development
Tirzepatide, marketed as Mounjaro for type 2 diabetes and Zepbound for obesity, introduces an additional mechanism by activating both GLP-1 and GIP receptors , which may amplify metabolic benefits
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The World Health Organization's December 2025 guidelines emphasized the importance of resistance training to protect muscle mass during GLP-1 therapy, acknowledging this as a limitation of current treatment approaches [49]
