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104 Furthermore, a mitochondrial injury may play a role in transitioning from diabetes to AD, as exposing diabetic rats brain mitochondria to A increases their vulnerability
Garber AJ, Duncan TG, Goodman AM, Mills DJ, Rohlf JL Efficacy of metformin in type II diabetes: Results of a double-blind, placebo-controlled, dose-response trial

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Over-suppression of cholesterol